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SKU:BT-MCA1140

SMC1 Monoclonal Antibody

SMC1 Monoclonal Antibody

Regular price $300.00 USD
Regular price Sale price $300.00 USD
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Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome.

Introducing the SMC1 Monoclonal Antibody, a cutting-edge biotechnological product designed to revolutionize the field of molecular biology. This meticulously crafted antibody is meticulously engineered to specifically target and bind to the Structural Maintenance of Chromosomes 1 (SMC1) protein, enabling researchers to delve deeper into the intricate mechanisms governing chromosomal maintenance and DNA repair.

The SMC1 Monoclonal Antibody boasts exceptional specificity and sensitivity, ensuring accurate and reliable results in a wide range of applications. Its high affinity for the SMC1 protein guarantees precise detection and quantification, facilitating comprehensive analysis of cellular processes such as DNA replication, recombination, and cell cycle regulation.

Crafted with utmost precision, this antibody undergoes rigorous quality control measures to ensure batch-to-batch consistency and reproducibility. Its exceptional performance is further enhanced by its compatibility with various experimental techniques, including immunofluorescence, immunohistochemistry, and Western blotting, enabling seamless integration into diverse research workflows.

Moreover, the SMC1 Monoclonal Antibody is manufactured using state-of-the-art techniques and adheres to the highest industry standards, ensuring exceptional purity and stability. Its long shelf life guarantees prolonged usability, allowing researchers to conduct experiments with confidence and convenience.

In summary, the SMC1 Monoclonal Antibody represents a breakthrough in molecular biology research, offering unparalleled specificity, sensitivity, and versatility. With its exceptional performance and reliability, this antibody is poised to empower scientists and researchers in unraveling the complexities of chromosomal maintenance and DNA repair, ultimately advancing our understanding of fundamental biological processes.

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