Shh Monoclonal Antibody

This gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a d

Introducing the SHH Monoclonal Antibody, a highly effective and reliable solution for the detection and analysis of Sonic Hedgehog (SHH) protein. This innovative product is designed to specifically target and bind to the SHH protein, allowing for accurate and precise identification and quantification of this important biomolecule.

The SHH Monoclonal Antibody is produced using state-of-the-art technology and rigorous quality control measures, ensuring consistent and reproducible results. It is suitable for use in a wide range of applications, including western blotting, immunohistochemistry, and flow cytometry.

With its exceptional sensitivity and specificity, the SHH Monoclonal Antibody is an essential tool for researchers and scientists working in the fields of developmental biology, cancer research, and stem cell biology. Its ability to detect and quantify SHH protein levels with high precision and accuracy makes it an invaluable asset in the pursuit of new discoveries and breakthroughs.

In summary, the SHH Monoclonal Antibody is a cutting-edge product that offers unparalleled performance and reliability in the detection and analysis of SHH protein. Its exceptional quality and versatility make it an indispensable tool for any researcher or scientist seeking to advance their understanding of this critical biomolecule.