RAG-2 Monoclonal Antibody

This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. 

The RAG-2 Monoclonal Antibody is a highly specific and sensitive tool for the detection and quantification of RAG-2 protein expression in various biological samples. This antibody is produced using advanced monoclonal antibody technology and has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and flow cytometry.

The RAG-2 Monoclonal Antibody is designed to recognize and bind to the RAG-2 protein, which is a key component of the V(D)J recombination machinery that plays a critical role in the development and maturation of B and T cells. This antibody is highly specific for RAG-2 and does not cross-react with other related proteins, ensuring accurate and reliable results.

This antibody is supplied in a convenient and easy-to-use format, with a range of sizes and concentrations available to suit different experimental needs. It is also provided with detailed instructions for use, including recommended dilutions and protocols for various applications.

Overall, the RAG-2 Monoclonal Antibody is a valuable tool for researchers studying the role of RAG-2 in immune system development and function. Its high specificity and sensitivity make it an ideal choice for a wide range of applications, and its ease of use and reliability make it a valuable addition to any laboratory.