PERK Monoclonal Antibody

The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

The PERK Monoclonal Antibody is a highly specialized and advanced product that has been developed to target and neutralize the protein kinase RNA-like endoplasmic reticulum kinase (PERK). This monoclonal antibody is designed to specifically bind to the PERK protein, which is a key regulator of the unfolded protein response (UPR) pathway. The UPR pathway is a critical cellular mechanism that helps to maintain protein homeostasis and prevent cellular stress.

The PERK Monoclonal Antibody is a powerful tool for researchers and scientists who are studying the UPR pathway and its role in various diseases and conditions. This product has been extensively tested and validated for its specificity and efficacy in a range of applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The PERK Monoclonal Antibody is manufactured to the highest standards of quality and purity, ensuring that researchers can rely on consistent and reproducible results. This product is available in a range of sizes and formats to suit different experimental needs, and is supplied with detailed protocols and technical support to ensure optimal performance.

Overall, the PERK Monoclonal Antibody is a cutting-edge product that represents a significant advance in the field of UPR pathway research. Its specificity, efficacy, and reliability make it an essential tool for scientists and researchers who are working to understand the complex mechanisms that underlie cellular stress and disease.