PDH-E1 Alpha Monoclonal Antibody

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Introducing the PDH-E1 Alpha Monoclonal Antibody, a cutting-edge product designed to revolutionize the field of immunology. This highly advanced antibody is meticulously engineered to target and bind specifically to the PDH-E1 protein, offering unparalleled precision and efficacy in various research applications.

The PDH-E1 Alpha Monoclonal Antibody boasts exceptional specificity, ensuring minimal cross-reactivity with other proteins, thus guaranteeing accurate and reliable results. Its superior affinity for the PDH-E1 protein enables robust detection and quantification, facilitating comprehensive analysis and interpretation of experimental data.

Crafted with utmost care and utilizing state-of-the-art technology, this antibody exhibits exceptional stability and consistency, ensuring reproducibility across experiments. Its exceptional purity and low endotoxin levels further enhance its suitability for a wide range of applications, including Western blotting, immunohistochemistry, and flow cytometry.

Furthermore, the PDH-E1 Alpha Monoclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. Its long shelf life guarantees prolonged usability, making it an ideal choice for laboratories and research institutions seeking a reliable and cost-effective solution.

In summary, the PDH-E1 Alpha Monoclonal Antibody represents a groundbreaking advancement in the field of immunology. With its exceptional specificity, stability, and versatility, this product is poised to revolutionize research endeavors, enabling scientists to unravel the complexities of PDH-E1 protein function with unprecedented precision and accuracy.