P38 mouse Monoclonal Antibody(8C11)

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

The P38 Mouse Monoclonal Antibody (8C11) is a highly specific and reliable tool for various research applications. This antibody is derived from a mouse source and has been extensively validated for its exceptional performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) techniques.

With its superior specificity, the P38 Mouse Monoclonal Antibody (8C11) exhibits minimal cross-reactivity, ensuring accurate and precise results. It targets the P38 protein, a key regulator of cellular responses to stress and inflammation, making it an invaluable tool for investigating various signaling pathways and cellular processes.

The P38 Mouse Monoclonal Antibody (8C11) is manufactured using state-of-the-art techniques, ensuring high purity and consistency. It is supplied in a convenient liquid format, allowing for easy handling and storage. The antibody is provided in a 100μg vial, enabling multiple experiments and reducing the need for frequent reordering.

This product is suitable for use in a wide range of species, including human, mouse, and rat, making it versatile for different experimental models. It has been extensively tested and validated in various cell lines and tissues, guaranteeing reliable and reproducible results.

In summary, the P38 Mouse Monoclonal Antibody (8C11) is a highly specific and reliable tool for researchers in the field of cellular signaling and inflammation. Its exceptional performance in IHC, IF, and WB techniques, along with its versatility and consistent quality, make it an essential component of any laboratory's research arsenal.