NSD1 Monoclonal Antibody

This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11.

The NSD1 Monoclonal Antibody is a highly specific and sensitive tool for the detection and analysis of NSD1 protein expression in various biological samples. This antibody is produced using advanced monoclonal antibody technology and has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. The NSD1 Monoclonal Antibody is designed to recognize the NSD1 protein with high affinity and specificity, making it an ideal tool for researchers and clinicians studying the role of NSD1 in various diseases and disorders. This antibody is available in various sizes and formats to suit different experimental needs and can be used in a wide range of research applications, including cancer research, developmental biology, and neuroscience. With its high specificity and sensitivity, the NSD1 Monoclonal Antibody is a valuable tool for researchers and clinicians seeking to better understand the role of NSD1 in various biological processes and diseases.