SKU:BT-MCA0711
Histone H3 Monoclonal Antibody
Histone H3 Monoclonal Antibody
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Introducing the Histone H3 Monoclonal Antibody, a highly specific and sensitive tool for the detection and analysis of histone H3 protein in various biological samples. This antibody is produced using advanced monoclonal antibody technology, ensuring high purity and consistency in every batch.
The Histone H3 Monoclonal Antibody is designed to recognize and bind to the N-terminal region of histone H3, a highly conserved protein that plays a crucial role in chromatin structure and gene regulation. This antibody has been extensively validated for use in a wide range of applications, including western blotting, immunoprecipitation, immunofluorescence, and chromatin immunoprecipitation (ChIP).
With its exceptional sensitivity and specificity, the Histone H3 Monoclonal Antibody is an essential tool for researchers studying epigenetics, gene expression, and chromatin biology. Its high affinity and selectivity make it ideal for use in a variety of research settings, including basic research, drug discovery, and clinical diagnostics.
In summary, the Histone H3 Monoclonal Antibody is a reliable and effective tool for the detection and analysis of histone H3 protein. Its exceptional sensitivity and specificity make it an essential tool for researchers studying chromatin biology and gene regulation. Order now and experience the benefits of this advanced monoclonal antibody technology.