Histone H3 (Di Methyl Lys36) Monoclonal Antibody(1E6)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

The HISTONE H3 (DI METHYL LYS36) MONOCLONAL ANTIBODY(1E6) is a highly specialized and meticulously developed product that serves as an invaluable tool for researchers in the field of molecular biology. This monoclonal antibody, with its exceptional specificity and sensitivity, is designed to target and detect the histone H3 protein, specifically the di methyl lysine 36 modification.

Crafted with utmost precision, this antibody exhibits exceptional affinity towards the di methyl lysine 36 modification of histone H3, enabling accurate and reliable detection in various experimental applications. Its monoclonal nature ensures batch-to-batch consistency, guaranteeing reproducible results and minimizing experimental variability.

The HISTONE H3 (DI METHYL LYS36) MONOCLONAL ANTIBODY(1E6) is meticulously validated through rigorous quality control measures, ensuring its superior performance and reliability. It has been extensively tested in a wide range of applications, including chromatin immunoprecipitation (ChIP), immunofluorescence, and western blotting, among others.

Researchers can confidently rely on this antibody to provide precise and reproducible results, facilitating their investigations into the intricate mechanisms of gene regulation and chromatin remodeling. Its exceptional sensitivity allows for the detection of even low abundance targets, enabling the exploration of subtle molecular events.

With its exceptional specificity, sensitivity, and reliability, the HISTONE H3 (DI METHYL LYS36) MONOCLONAL ANTIBODY(1E6) is an indispensable tool for researchers seeking to unravel the complexities of epigenetic modifications and their impact on gene expression.