Histone H3 (Di Methyl Lys27) Monoclonal Antibody(1A8)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

The HISTONE H3 (DI METHYL LYS27) MONOCLONAL ANTIBODY(1A8) is a highly specialized and meticulously developed product that serves as an essential tool in the field of molecular biology and research. This monoclonal antibody, specifically designed to target the histone H3 protein with a dimethylated lysine residue at position 27, offers unparalleled precision and accuracy in detecting and analyzing epigenetic modifications.

Crafted with utmost care and expertise, this antibody exhibits exceptional specificity and sensitivity, ensuring reliable and reproducible results in various experimental applications. Its monoclonal nature guarantees batch-to-batch consistency, eliminating any concerns regarding variability and ensuring consistent performance throughout experiments.

The HISTONE H3 (DI METHYL LYS27) MONOCLONAL ANTIBODY(1A8) is meticulously validated through rigorous quality control measures, including Western blotting, immunohistochemistry, and immunofluorescence assays. These comprehensive assessments ensure its reliability and suitability for a wide range of experimental techniques, enabling researchers to delve into the intricate world of epigenetic modifications with confidence.

This antibody's exceptional performance is further enhanced by its compatibility with multiple species, including human, mouse, and rat, broadening its applicability and facilitating cross-species research. Its versatility extends to various sample types, including cell lines, tissues, and biological fluids, enabling researchers to explore diverse biological systems and unravel the complexities of epigenetic regulation.

In summary, the HISTONE H3 (DI METHYL LYS27) MONOCLONAL ANTIBODY(1A8) stands as a pinnacle of scientific innovation, offering researchers an indispensable tool to investigate and comprehend the intricate mechanisms of epigenetic modifications. With its exceptional specificity, sensitivity, and compatibility, this antibody empowers researchers to unlock new insights and advance our understanding of the fundamental processes governing gene expression and cellular function.