E-cadherin Monoclonal Antibody

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.

Introducing the E-Cadherin Monoclonal Antibody, a highly effective and reliable solution for the detection and analysis of E-Cadherin protein expression. This antibody is specifically designed to target and bind to the E-Cadherin protein, a crucial component of cell-cell adhesion and tissue integrity.

The E-Cadherin Monoclonal Antibody is produced using advanced technology and rigorous quality control measures to ensure optimal performance and consistency. It is suitable for a wide range of applications, including immunohistochemistry, western blotting, and flow cytometry.

With its high specificity and sensitivity, the E-Cadherin Monoclonal Antibody is an essential tool for researchers and clinicians in the fields of cancer biology, developmental biology, and tissue engineering. It enables accurate and precise detection of E-Cadherin expression in various tissues and cell types, facilitating the identification of potential biomarkers and therapeutic targets.

In summary, the E-Cadherin Monoclonal Antibody is a top-quality product that offers exceptional performance and versatility. It is an indispensable tool for anyone working in the field of cell biology and molecular biology, and it is sure to deliver reliable and reproducible results every time.