Dynactin 1 Monoclonal Antibody

This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA).

Introducing the DYNACTIN 1 Monoclonal Antibody, a cutting-edge scientific tool designed to revolutionize research in the field of cellular biology. This meticulously crafted antibody is specifically engineered to target and bind to the DYNACTIN 1 protein, enabling researchers to gain invaluable insights into its intricate functions and mechanisms within the cell.

With its exceptional specificity and high affinity, the DYNACTIN 1 Monoclonal Antibody guarantees accurate and reliable results, ensuring the utmost precision in experimental analyses. Its superior performance is further enhanced by its exceptional sensitivity, enabling the detection of even the most minute quantities of DYNACTIN 1 protein, thus facilitating comprehensive investigations into its role in cellular processes.

Crafted with utmost care and precision, this antibody undergoes rigorous quality control measures to ensure its purity, potency, and consistency. Its exceptional stability and long shelf life make it an ideal choice for long-term experiments, providing researchers with a reliable and consistent tool for their scientific endeavors.

The DYNACTIN 1 Monoclonal Antibody is compatible with a wide range of experimental techniques, including immunofluorescence, immunohistochemistry, and Western blotting, allowing researchers to explore the localization, expression, and interactions of DYNACTIN 1 protein with unparalleled accuracy and efficiency.

In summary, the DYNACTIN 1 Monoclonal Antibody represents a breakthrough in cellular biology research, offering scientists an indispensable tool to unravel the complexities of DYNACTIN 1 protein and its vital role in cellular processes. With its exceptional specificity, sensitivity, and compatibility with various experimental techniques, this antibody is poised to revolutionize the field, empowering researchers to make significant strides in understanding cellular biology at a molecular level.