CTCF Monoclonal Antibody

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been

Introducing the CTCF Monoclonal Antibody, a highly specific and sensitive tool for the detection and analysis of the CTCF protein. This antibody has been rigorously tested and validated for use in a variety of applications, including Western blotting, immunoprecipitation, and immunofluorescence microscopy.

The CTCF Monoclonal Antibody is produced using state-of-the-art techniques and is of the highest quality, ensuring reliable and reproducible results. It recognizes the CTCF protein with exceptional specificity, allowing for accurate detection and quantification of this important transcription factor.

This antibody is suitable for use in a wide range of research areas, including gene regulation, chromatin structure, and epigenetics. Its high sensitivity and specificity make it an ideal tool for studying the role of CTCF in various biological processes.

In summary, the CTCF Monoclonal Antibody is a valuable addition to any researcher's toolkit, providing reliable and accurate detection of the CTCF protein in a variety of applications. Its high quality and specificity make it an essential tool for studying the role of CTCF in gene regulation and chromatin structure.