Collagen I mouse Monoclonal Antibody(4H10)

This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

The COLLAGEN I MOUSE MONOCLONAL ANTIBODY(4H10) is a highly specific and reliable tool for the detection and analysis of collagen I in various biological samples. This monoclonal antibody is derived from mouse and exhibits exceptional affinity towards collagen I, making it an ideal choice for researchers and scientists working in the field of collagen biology.

With its superior sensitivity and specificity, the COLLAGEN I MOUSE MONOCLONAL ANTIBODY(4H10) enables accurate and precise quantification of collagen I levels in tissues, cells, and extracellular matrices. Its robust performance ensures consistent and reproducible results, facilitating reliable data interpretation and analysis.

The COLLAGEN I MOUSE MONOCLONAL ANTIBODY(4H10) is manufactured using state-of-the-art techniques, ensuring high purity and quality. It has been extensively validated for various applications, including immunohistochemistry, immunofluorescence, Western blotting, and ELISA. Its versatility allows for a wide range of experimental designs and applications, providing researchers with flexibility and convenience.

Furthermore, this antibody exhibits minimal cross-reactivity with other collagen types, ensuring specific detection of collagen I without interference from other collagen isoforms. Its exceptional selectivity enhances the accuracy and reliability of experimental results, enabling researchers to gain valuable insights into collagen I-related processes and pathologies.

The COLLAGEN I MOUSE MONOCLONAL ANTIBODY(4H10) is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided in a liquid form, eliminating the need for reconstitution and ensuring immediate usability. The antibody is stable under recommended storage conditions, ensuring long-term reliability and performance.

In summary, the COLLAGEN I MOUSE MONOCLONAL ANTIBODY(4H10) is a highly specific, sensitive, and reliable tool for the detection and analysis of collagen I. Its exceptional performance, versatility, and convenience make it an indispensable asset for researchers and scientists studying collagen biology and related fields.