Clock Monoclonal Antibody

The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants.

The CLOCK Monoclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of the CLOCK protein in various biological samples. This antibody is produced using advanced monoclonal antibody technology, ensuring exceptional quality and consistency.

The CLOCK protein plays a crucial role in regulating circadian rhythms and controlling the expression of numerous genes involved in various physiological processes. With its ability to bind specifically to the CLOCK protein, this monoclonal antibody enables researchers to investigate the intricate mechanisms underlying circadian rhythm regulation.

The CLOCK Monoclonal Antibody exhibits exceptional sensitivity and specificity, making it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its high affinity for the CLOCK protein ensures accurate and reliable results, facilitating precise quantification and localization studies.

This antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into experimental workflows. Its robust performance and consistent results make it an indispensable tool for researchers studying circadian rhythms, gene expression, and related fields.

Choose the CLOCK Monoclonal Antibody for its exceptional quality, reliability, and versatility, and unlock new insights into the intricate mechanisms governing circadian rhythms and gene expression.