SKU:BT-MCA0272
CD105 Monoclonal Antibody
CD105 Monoclonal Antibody
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
The CD105 Monoclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CD105 expression in various biological samples. This antibody is produced using advanced monoclonal antibody technology, ensuring exceptional quality and consistency.
CD105, also known as endoglin, is a transmembrane glycoprotein that plays a crucial role in angiogenesis and vascular development. It is predominantly expressed on endothelial cells and is involved in regulating cell proliferation, migration, and differentiation. The CD105 Monoclonal Antibody binds specifically to CD105, allowing for accurate identification and quantification of CD105-positive cells.
This antibody is suitable for a wide range of applications, including flow cytometry, immunohistochemistry, and western blotting. It exhibits high sensitivity and specificity, enabling precise and reliable results. The CD105 Monoclonal Antibody is validated for use in human samples and has been extensively tested to ensure optimal performance.
With its exceptional quality and reliability, the CD105 Monoclonal Antibody is an indispensable tool for researchers and clinicians studying angiogenesis, vascular biology, and related fields. Its use can contribute to a deeper understanding of CD105-mediated processes and aid in the development of novel therapeutic strategies targeting CD105.