Calregulin Monoclonal Antibody

Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element. Calreticulin can inhibit the binding of androgen receptor to its

Introducing the CALREGULIN Monoclonal Antibody, a cutting-edge scientific breakthrough in the field of immunology. This meticulously developed product is designed to target and neutralize the CALREGULIN protein, a key regulator of cellular calcium homeostasis.

Crafted with utmost precision and utilizing state-of-the-art technology, this monoclonal antibody offers unparalleled specificity and efficacy. Its high affinity for CALREGULIN ensures optimal binding, resulting in the inhibition of aberrant calcium signaling pathways.

The CALREGULIN Monoclonal Antibody boasts exceptional purity, having undergone rigorous purification processes to eliminate impurities and contaminants. This guarantees a reliable and consistent performance, making it an ideal choice for a wide range of research applications.

With its versatile nature, this antibody can be employed in various experimental settings, including immunohistochemistry, western blotting, and flow cytometry. Its exceptional sensitivity and specificity enable accurate detection and quantification of CALREGULIN expression levels, facilitating comprehensive analysis and interpretation of experimental data.

Furthermore, the CALREGULIN Monoclonal Antibody is manufactured in compliance with stringent quality control measures, ensuring batch-to-batch consistency and reproducibility. Each vial is meticulously tested to meet the highest standards, guaranteeing reliable and reproducible results.

In summary, the CALREGULIN Monoclonal Antibody represents a groundbreaking tool for researchers and scientists alike, offering unrivaled precision, reliability, and versatility. Unlock the potential of CALREGULIN research with this exceptional product and pave the way for new discoveries in the field of immunology.