Bmi-1 Monoclonal Antibody

This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.

The BMI-1 Monoclonal Antibody is a highly specific and sensitive tool for the detection and quantification of BMI-1 protein expression in various biological samples. This antibody is produced using advanced monoclonal antibody technology and has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and flow cytometry.

The BMI-1 protein is a key regulator of stem cell self-renewal and plays a critical role in the development and progression of various cancers. The BMI-1 Monoclonal Antibody is designed to specifically recognize and bind to the BMI-1 protein, enabling researchers to study its expression and function in various biological systems.

This antibody is supplied in a convenient and easy-to-use format, with a high degree of reproducibility and consistency between batches. It is suitable for use in a wide range of research applications, including basic research, drug discovery, and clinical diagnostics.

Overall, the BMI-1 Monoclonal Antibody is a valuable tool for researchers studying the role of BMI-1 in stem cell biology and cancer, and is an essential component of any research program focused on understanding the molecular mechanisms underlying these complex processes.