a-actinin Monoclonal Antibody(4A12)

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Introducing the A-Actinin Monoclonal Antibody (4A12), a cutting-edge product designed to revolutionize the field of molecular biology. This highly specific antibody is meticulously engineered to target and detect A-actinin, a crucial protein involved in various cellular processes.

The A-Actinin Monoclonal Antibody (4A12) boasts exceptional sensitivity and selectivity, enabling researchers to accurately visualize and quantify A-actinin expression in a wide range of biological samples. Its monoclonal nature ensures consistent and reproducible results, making it an invaluable tool for both basic research and clinical applications.

With its advanced technology, this antibody offers unparalleled versatility. It can be utilized in various experimental techniques, including immunofluorescence, immunohistochemistry, and Western blotting. Its compatibility with multiple species, including human, mouse, and rat, further enhances its utility across diverse research settings.

The A-Actinin Monoclonal Antibody (4A12) is manufactured under stringent quality control measures, guaranteeing exceptional purity and reliability. Its long shelf life ensures prolonged usability, minimizing the need for frequent reordering and reducing experimental variability.

In summary, the A-Actinin Monoclonal Antibody (4A12) is a state-of-the-art product that promises to revolutionize A-actinin research. Its exceptional sensitivity, versatility, and reliability make it an indispensable tool for scientists and clinicians alike. Stay at the forefront of molecular biology with this groundbreaking antibody.