IDE Monoclonal Antibody(3H4)

This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been describe

The IDE Monoclonal Antibody (3H4) is a highly specific and reliable tool for the detection and quantification of insulin-degrading enzyme (IDE) in various biological samples. This monoclonal antibody is produced using advanced hybridoma technology, ensuring consistent and reproducible results.

The IDE Monoclonal Antibody (3H4) exhibits exceptional affinity and selectivity towards IDE, making it an ideal choice for research and diagnostic applications. It has been extensively validated and characterized for its specificity, sensitivity, and stability, guaranteeing accurate and precise measurements.

This antibody is supplied in a ready-to-use format, allowing for convenient and efficient experimentation. It can be utilized in various immunoassays, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assays (ELISA). Its versatility enables researchers to explore IDE expression and activity in different tissues and cell types.

The IDE Monoclonal Antibody (3H4) is manufactured under strict quality control standards to ensure batch-to-batch consistency and reliability. It is provided in a liquid formulation, eliminating the need for reconstitution and minimizing the risk of sample contamination.

With its exceptional performance and ease of use, the IDE Monoclonal Antibody (3H4) is an indispensable tool for scientists and clinicians studying IDE-related processes and diseases. Its high specificity and sensitivity make it an invaluable asset in the field of insulin metabolism research, offering valuable insights into the regulation and function of IDE.