ZDH17 Polyclonal Antibody

Catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.,The DHHC domain is required for palmitoyltransferase activity.,Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HD. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. May be involved in the NF-kappa-B signaling pathway. Has transforming activity.,miscellaneous:The early and prominent pathology of HD is observed in the medium spiny neurons that project into the globus.,Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.,Contains 1 DHHC-type zinc finger.,Contains 5 ANK repeats.,subunit:Binds HD. This interaction is inversely correlated to the length of the polyglutamine tract added to the huntingtin protein in Huntington disease.,tissue specificity:Expressed in all brain regions. Expression is highest in the cortex, cerebellum, occipital lobe and caudate and lowest in the spinal cord. Expression is also seen in testis, pancreas, heart and kidney.

The ZDH17 Polyclonal Antibody is a highly specific and reliable tool designed for various applications in the field of biomedical research. This antibody is produced using advanced techniques, ensuring exceptional quality and performance. With its polyclonal nature, it exhibits a broad spectrum of reactivity, making it suitable for a wide range of targets.

The ZDH17 Polyclonal Antibody demonstrates exceptional sensitivity and specificity, enabling accurate detection and quantification of the target protein. Its superior affinity and avidity ensure optimal binding, resulting in reliable and reproducible results. This antibody is meticulously validated to guarantee consistent performance across different experimental conditions.

This antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided in a liquid formulation, eliminating the need for reconstitution, and is compatible with various assay formats, including Western blotting, immunohistochemistry, and immunofluorescence. Its versatility makes it an indispensable tool for researchers in diverse fields.

The ZDH17 Polyclonal Antibody is manufactured in compliance with stringent quality control standards, ensuring batch-to-batch consistency and reliability. It undergoes rigorous testing to confirm its specificity, sensitivity, and performance, providing researchers with confidence in their experimental results.

In summary, the ZDH17 Polyclonal Antibody is a highly specific, reliable, and versatile tool for biomedical research. Its exceptional quality, sensitivity, and compatibility with various assay formats make it an invaluable asset for scientists seeking accurate and reproducible results.