ZAP-70(Phospho Tyr319) Polyclonal Antibody

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

The ZAP-70(PHOSPHO TYR319) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of ZAP-70 protein phosphorylated at tyrosine 319. This antibody is produced using advanced polyclonal antibody production techniques, ensuring high affinity and specificity towards the target antigen.

ZAP-70 is a critical protein involved in T-cell receptor signaling and plays a crucial role in the activation and regulation of T-cells. Phosphorylation of ZAP-70 at tyrosine 319 is a key event in the activation of T-cells and is associated with various immune disorders and diseases.

The ZAP-70(PHOSPHO TYR319) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, immunofluorescence, and flow cytometry. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated ZAP-70 at tyrosine 319.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing wastage. The product is quality-controlled to meet the highest standards, ensuring consistent and reproducible results.

The ZAP-70(PHOSPHO TYR319) Polyclonal Antibody is an indispensable tool for researchers and scientists studying T-cell signaling pathways, immune disorders, and related diseases. Its high specificity and sensitivity make it an ideal choice for both basic research and clinical applications.

Order your ZAP-70(PHOSPHO TYR319) Polyclonal Antibody today and unlock new insights into T-cell biology and immune system regulation.