YB-1(Phospho Ser102) Polyclonal Antibody

This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.

The YB-1(PHOSPHO SER102) Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of YB-1 protein phosphorylated at serine 102 residue. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the phosphorylated serine 102 region of the YB-1 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the phosphorylated YB-1 protein, making it an ideal tool for various applications in research and diagnostics.

The YB-1(PHOSPHO SER102) Polyclonal Antibody is suitable for use in various immunoassays, including Western blotting, immunohistochemistry, and ELISA. It has been validated for use in human, mouse, and rat samples, and has been shown to exhibit minimal cross-reactivity with non-phosphorylated YB-1 protein or other related proteins. The antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

In summary, the YB-1(PHOSPHO SER102) Polyclonal Antibody is a reliable and high-quality reagent that can be used for the detection and quantification of phosphorylated YB-1 protein in various biological samples. Its high specificity and sensitivity make it an essential tool for researchers and clinicians working in the fields of cancer biology, signal transduction, and molecular diagnostics.