VE-Cadherin Polyclonal Antibody

This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.

The VE-Cadherin Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of VE-Cadherin protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity.

VE-Cadherin, also known as vascular endothelial cadherin or CDH5, is a transmembrane glycoprotein that plays a crucial role in the maintenance of endothelial cell integrity and vascular development. It is predominantly expressed in endothelial cells and is involved in cell-cell adhesion, regulating vascular permeability, and angiogenesis.

The VE-Cadherin Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes the native and denatured forms of VE-Cadherin protein, enabling accurate and reliable detection in both normal and pathological tissues.

This antibody has been extensively validated and characterized to ensure consistent and reproducible results. It exhibits minimal cross-reactivity with other related proteins, ensuring specificity in target detection. Additionally, it demonstrates excellent sensitivity, allowing for the detection of low levels of VE-Cadherin expression.

The VE-Cadherin Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and complex preparation steps. It is provided in a convenient format, allowing for easy storage and handling.

In summary, the VE-Cadherin Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of VE-Cadherin protein expression. With its exceptional performance and ease of use, it is an essential reagent for researchers and scientists studying vascular biology, angiogenesis, and endothelial cell function.