VDR(Phospho Ser208) Polyclonal Antibody

This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.

The VDR(PHOSPHO SER208) Polyclonal Antibody is a highly specialized and meticulously crafted product designed to facilitate advanced research in the field of molecular biology. This antibody is specifically tailored to target the phosphorylated serine 208 residue of the Vitamin D Receptor (VDR), enabling precise detection and analysis of this crucial protein modification.

With its exceptional specificity and sensitivity, this polyclonal antibody offers researchers an invaluable tool for investigating the intricate signaling pathways and regulatory mechanisms involving VDR. By selectively binding to the phosphorylated serine 208 site, this antibody allows for the identification and quantification of phosphorylation events, shedding light on the dynamic nature of VDR function.

Manufactured using state-of-the-art techniques and quality-controlled processes, this antibody guarantees reproducibility and reliability in experimental results. Its high affinity and low background ensure accurate and robust detection, enabling researchers to obtain precise and meaningful data.

The VDR(PHOSPHO SER208) Polyclonal Antibody is suitable for a wide range of applications, including Western blotting, immunoprecipitation, immunofluorescence, and immunohistochemistry. Its versatility allows for comprehensive investigations into VDR phosphorylation dynamics across various experimental setups and sample types.

In summary, the VDR(PHOSPHO SER208) Polyclonal Antibody is an indispensable tool for researchers seeking to unravel the intricate mechanisms underlying VDR signaling. Its exceptional specificity, reliability, and versatility make it an essential component of any molecular biology laboratory, facilitating groundbreaking discoveries and advancing our understanding of cellular processes.