Vav3(Phospho Tyr173) Polyclonal Antibody

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

The VAV3(PHOSPHO TYR173) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of VAV3 protein phosphorylated at tyrosine 173. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and sensitivity.

The VAV3 protein plays a crucial role in various cellular processes, including signal transduction, cell proliferation, and differentiation. Phosphorylation of tyrosine 173 is a key post-translational modification that regulates the activity and function of VAV3. Therefore, the VAV3(PHOSPHO TYR173) Polyclonal Antibody is an essential tool for researchers studying the molecular mechanisms underlying these processes.

This antibody has been extensively validated for its specificity and sensitivity in various experimental techniques, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with other proteins, ensuring accurate and reliable results.

The VAV3(PHOSPHO TYR173) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering.

For optimal results, it is recommended to follow the provided protocols and guidelines for sample preparation, antibody dilution, and detection methods. The antibody should be stored at -20°C to maintain its stability and activity.

In summary, the VAV3(PHOSPHO TYR173) Polyclonal Antibody is a valuable tool for researchers investigating the role of VAV3 protein phosphorylation in cellular processes. Its high specificity, sensitivity, and ease of use make it an ideal choice for reliable and accurate experimental results.