Vav(Phospho Tyr160) Polyclonal Antibody

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Introducing the VAV(PHOSPHO TYR160) Polyclonal Antibody, a highly effective and reliable product designed for use in various research applications. This antibody is specifically designed to target the phosphorylated tyrosine residue at position 160 of the VAV protein, making it an ideal tool for studying the activation and regulation of VAV signaling pathways.

The VAV(PHOSPHO TYR160) Polyclonal Antibody is produced using state-of-the-art techniques and is rigorously tested to ensure its purity, specificity, and sensitivity. It is suitable for use in a variety of applications, including Western blotting, immunoprecipitation, and immunofluorescence.

This antibody is supplied in a convenient format, with ample quantities available for multiple experiments. It is also provided with detailed instructions for use, ensuring that researchers can achieve optimal results with ease.

In summary, the VAV(PHOSPHO TYR160) Polyclonal Antibody is a high-quality product that offers exceptional performance and reliability. It is an essential tool for researchers studying VAV signaling pathways and is sure to deliver accurate and reproducible results.