Trk A(Phospho Tyr680/Y681) Polyclonal Antibody

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

The TRK A(PHOSPHO TYR680/Y681) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated tyrosine residues at positions 680 and 681 on the TRK A protein. This antibody is produced using a polyclonal approach, ensuring a diverse range of binding sites and enhanced sensitivity for accurate detection.

With its exceptional specificity, this antibody enables researchers to investigate the activation and signaling pathways of TRK A, a receptor tyrosine kinase involved in various cellular processes such as cell growth, differentiation, and survival. By targeting the phosphorylated tyrosine residues at positions 680 and 681, this antibody allows for precise monitoring of TRK A activation and downstream signaling events.

The TRK A(PHOSPHO TYR680/Y681) Polyclonal Antibody is rigorously validated for use in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. Its high affinity and selectivity ensure reliable and reproducible results, making it an indispensable tool for researchers studying TRK A signaling pathways and associated diseases.

This antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into experimental workflows. It is provided in a liquid formulation, ensuring stability and ease of handling. Additionally, it is available in different sizes to accommodate various experimental needs.

Choose the TRK A(PHOSPHO TYR680/Y681) Polyclonal Antibody for its exceptional specificity, sensitivity, and versatility, and unlock new insights into the intricate mechanisms of TRK A signaling.