Topo II alpha(Phospho Thr1343) Polyclonal Antibody

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also pla

The TOPO II ALPHA(PHOSPHO THR1343) Polyclonal Antibody is a highly specialized and meticulously developed product designed for advanced scientific research. This antibody is specifically designed to target and detect the phosphorylated form of the threonine residue at position 1343 on the TOPO II ALPHA protein.

With its exceptional specificity and sensitivity, this polyclonal antibody offers researchers a valuable tool for investigating the intricate mechanisms and functions of TOPO II ALPHA in various biological processes. Its unique ability to recognize and bind to the phosphorylated form of TOPO II ALPHA at Thr1343 enables precise and accurate detection, ensuring reliable and reproducible results.

Manufactured using state-of-the-art techniques and quality-controlled processes, this antibody guarantees exceptional performance and reliability. Its high affinity and selectivity make it an ideal choice for a wide range of applications, including immunoblotting, immunoprecipitation, and immunofluorescence assays.

Furthermore, this TOPO II ALPHA(PHOSPHO THR1343) Polyclonal Antibody has been extensively validated and tested to ensure its superior performance and consistency. It exhibits minimal cross-reactivity with other proteins, ensuring specific and reliable detection of the phosphorylated form of TOPO II ALPHA at Thr1343.

In summary, the TOPO II ALPHA(PHOSPHO THR1343) Polyclonal Antibody is a cutting-edge research tool that offers scientists unparalleled precision and accuracy in the study of TOPO II ALPHA. Its exceptional specificity, sensitivity, and reliability make it an indispensable asset for any laboratory conducting advanced scientific investigations.