TNKS2 Polyclonal Antibody

Catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.,May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length.,PTM:ADP-ribosylated (-auto).,Contains 1 PARP catalytic domain.,Contains 1 SAM (sterile alpha motif) domain.,Contains 15 ANK repeats.,subcellular location:Associated with the Golgi and with juxtanuclear SLC2A4/GLUT4-vesicles. Also found around the pericentriolar matrix of mitotic centromeres. During interphase, a small fraction of TNKS2 is found in the nucleus, associated with TRF1.,subunit:Oligomerizes and associates with TNKS. Interacts with the cytoplasmic domain of LNPEP/Otase in SLC2A4/GLUT4-vesicles. Binds to the N-terminus of Grb14 and TRF1 with its ankyrin repeat region.,tissue specificity:Highly expressed in placenta, skeletal muscle, liver, brain, kidney, heart, thymus, spinal cord, lung, peripheral blood leukocytes, pancreas, lymph nodes, spleen, prostate, testis, ovary, small intestine, colon, mammary gland, breast and breast carcinoma, and in common-type meningioma. Highly expressed in fetal liver, heart and brain.

The TNKS2 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of TNKS2 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity. With its exceptional performance, this antibody enables accurate and precise identification of TNKS2 protein in Western blotting, immunohistochemistry, and immunofluorescence applications.

The TNKS2 Polyclonal Antibody exhibits excellent specificity, exhibiting minimal cross-reactivity with other related proteins. This feature guarantees reliable and accurate results, minimizing false positives and ensuring the integrity of experimental data. Furthermore, this antibody demonstrates exceptional reproducibility, allowing for consistent and reliable results across multiple experiments.

This antibody is supplied as a liquid formulation, facilitating easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. The TNKS2 Polyclonal Antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and whole-cell lysates, making it suitable for diverse research applications.

In summary, the TNKS2 Polyclonal Antibody is a valuable tool for researchers studying TNKS2 protein expression. Its high specificity, sensitivity, and reproducibility ensure accurate and reliable results, enabling in-depth investigations into the role and function of TNKS2 in various biological processes.