TIAM1 Polyclonal Antibody

Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.,Belongs to the TIAM family.,Contains 1 DH (DBL-homology) domain.,Contains 1 PDZ (DHR) domain.,Contains 1 PH domain.,Contains 1 RBD (Ras-binding) domain.,Contains 2 PH domains.,subunit:Interacts with BAIAP2.,tissue specificity:Found in virtually all analyzed tumor cell lines including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.,

The TIAM1 Polyclonal Antibody is a meticulously crafted antibody that exhibits exceptional specificity and sensitivity, rendering it an invaluable asset for a multitude of research endeavors. Employing a polyclonal approach, this antibody guarantees an elevated level of specificity and sensitivity. Its primary function is to identify and bind to the TIAM1 protein, a prominent member of the Dbl family of guanine nucleotide exchange factors. This protein plays a pivotal role in the regulation of cell growth, differentiation, and migration, rendering it a crucial target for research in diverse fields, including cancer biology, neuroscience, and developmental biology.

The TIAM1 Polyclonal Antibody has undergone rigorous validation for employment in Western blotting, immunohistochemistry, and immunofluorescence assays. Furthermore, it is available in a range of sizes to cater to the diverse requirements of various research applications. With its unparalleled specificity and sensitivity, the TIAM1 Polyclonal Antibody serves as an indispensable tool for researchers endeavoring to unravel the intricate mechanisms underlying the involvement of TIAM1 in a myriad of biological processes.