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SKU:BT-AP14865

TERT(Phospho Ser824) Polyclonal Antibody

TERT(Phospho Ser824) Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative sp

The TERT(PHOSPHO SER824) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of TERT protein phosphorylated at serine 824. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The TERT(PHOSPHO SER824) Polyclonal Antibody exhibits outstanding performance in recognizing the phosphorylated form of TERT protein at serine 824, making it an invaluable tool for researchers studying telomerase regulation and its involvement in cellular processes such as cell proliferation, aging, and cancer development.

This antibody is meticulously manufactured using high-quality materials and undergoes rigorous quality control measures to ensure batch-to-batch consistency and reproducibility. It has been extensively validated in various experimental settings, demonstrating its reliability and accuracy in detecting TERT phosphorylation at serine 824.

With its exceptional specificity and sensitivity, the TERT(PHOSPHO SER824) Polyclonal Antibody offers researchers a reliable and precise tool for investigating the role of TERT phosphorylation in cellular signaling pathways and disease progression. Its versatility and compatibility with multiple applications make it an ideal choice for scientists working in diverse fields, including molecular biology, cancer research, and drug discovery.

Choose the TERT(PHOSPHO SER824) Polyclonal Antibody for its exceptional performance, reliability, and accuracy, and unlock new insights into the intricate mechanisms of telomerase regulation and its implications in various biological processes.

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