TBR1 Polyclonal Antibody

This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.

The TBR1 polyclonal antibody is a highly specific and reliable tool for the detection and analysis of TBR1 protein expression in various biological samples. This antibody has been meticulously developed and rigorously validated to ensure optimal performance and accuracy in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting applications.

The TBR1 polyclonal antibody exhibits exceptional sensitivity and specificity, enabling precise identification and localization of TBR1 protein in tissues and cells. It recognizes an epitope within the C-terminal region of TBR1, a transcription factor crucial for the development and function of the cerebral cortex.

With its superior affinity and selectivity, this antibody offers researchers a valuable tool for investigating the role of TBR1 in neurodevelopmental disorders, such as autism spectrum disorders and schizophrenia. Its robust performance and consistent results make it an indispensable asset for studies focused on understanding the molecular mechanisms underlying brain development and function.

The TBR1 polyclonal antibody is supplied as a liquid formulation, ensuring ease of use and convenience. It is provided in a ready-to-use format, eliminating the need for time-consuming and error-prone antibody dilutions. This product is available in various sizes to accommodate different experimental requirements.

In summary, the TBR1 polyclonal antibody is a highly reliable and specific reagent that enables accurate detection and analysis of TBR1 protein expression. Its exceptional performance and versatility make it an indispensable tool for researchers investigating the intricate processes of brain development and associated disorders.