TBCB Polyclonal Antibody

Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.,PTM:Phosphorylation by PAK1 is required for normal function. Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Ubiquitinated in the presence of GAN which targets it for degradation by the proteasome.,Belongs to the TBCB family.,Contains 1 CAP-Gly domain.,subcellular location:Colocalizes with microtubules. In differentiated neurons, located in the cytoplasm. In differentiating neurons, accumulates at the growth cone.,subunit:Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state. Cofactors B and E can form a heterodimer which binds to alpha-tubulin and enhances their ability to dissociate tubulin heterodimers. Binds to GAN.,tissue specificity:Found in most tissues.,

Introducing the TBCB Polyclonal Antibody, a cutting-edge product meticulously designed to cater to the diverse needs of the scientific community. This antibody, derived from a polyclonal source, exhibits exceptional specificity and sensitivity, making it an invaluable tool for various research applications.

The TBCB Polyclonal Antibody boasts a superior affinity towards its target, ensuring precise and reliable results. Its high-quality formulation guarantees consistent performance, enabling researchers to obtain accurate data with every experiment. This antibody is meticulously manufactured using state-of-the-art techniques, ensuring batch-to-batch reproducibility and minimizing any potential variability.

With its broad reactivity profile, the TBCB Polyclonal Antibody is suitable for a wide range of applications, including immunohistochemistry, western blotting, and immunofluorescence. Its versatility allows for seamless integration into various experimental protocols, facilitating comprehensive investigations across multiple disciplines.

Furthermore, the TBCB Polyclonal Antibody is rigorously validated to meet the highest industry standards. Its exceptional specificity ensures minimal cross-reactivity, guaranteeing reliable and specific results. This antibody's outstanding sensitivity enables the detection of even low-abundance targets, enhancing the scope of research possibilities.

The TBCB Polyclonal Antibody is packaged in a convenient and user-friendly format, ensuring ease of use and storage. Its long shelf life ensures prolonged usability, making it a cost-effective choice for laboratories of all sizes. Additionally, our dedicated customer support team is readily available to address any inquiries or concerns, ensuring a seamless experience for our esteemed customers.

In summary, the TBCB Polyclonal Antibody is a state-of-the-art product that combines exceptional specificity, sensitivity, and versatility. With its reliable performance and broad reactivity profile, this antibody is an indispensable tool for researchers seeking accurate and reproducible results. Choose the TBCB Polyclonal Antibody and unlock new possibilities in your scientific endeavors.