T2R38 Polyclonal Antibody

This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant).

The T2R38 Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the human T2R38 protein. The T2R38 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting T2R38 protein expression in various tissues and cell types.

This antibody is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to be highly effective in detecting T2R38 protein expression in human nasal epithelial cells, which is important for understanding the role of this protein in taste perception and respiratory health.

The T2R38 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a protein A column. It is provided in a liquid format, which makes it easy to use and store. This antibody is available in various sizes to meet the needs of different research applications.

Overall, the T2R38 Polyclonal Antibody is a reliable and high-quality tool for researchers studying the T2R38 protein and its role in various physiological processes. Its specificity and sensitivity make it an ideal choice for a wide range of applications, and its ease of use and storage make it a convenient option for laboratories of all sizes.