SYN3 Polyclonal Antibody

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite directi

The SYN3 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of SYN3 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a unique epitope of the human SYN3 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal tool for various applications in research and diagnostics.

The SYN3 Polyclonal Antibody has been extensively validated for its performance in Western blotting, immunohistochemistry, and immunofluorescence assays. It recognizes a single band of the expected molecular weight in Western blotting and shows strong staining in immunohistochemistry and immunofluorescence assays. The antibody has also been tested in various cell lines and tissues, including human brain, liver, and kidney, and has shown consistent and reliable results.

The SYN3 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum using a synthetic peptide column. The antibody is provided in a liquid format, which is ready to use for various applications. It is recommended to store the antibody at -20°C for long-term storage and avoid repeated freeze-thaw cycles.

In summary, the SYN3 Polyclonal Antibody is a highly specific and sensitive immunological reagent that can be used for the detection and quantification of SYN3 protein in various biological samples. Its high affinity and specificity make it an ideal tool for various applications in research and diagnostics.