SV2B Polyclonal Antibody

This gene encodes a member of the synaptic vesicle proteins 2 (SV2) family and major facilitator superfamily of proteins. This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis. Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons, and that this protein may be important for the integrity of the glomerular filtration barrier. This gene shows reduced expression in areas of synaptic loss in the hippocampus of human temporal lobe epilepsy patients.

The SV2B polyclonal antibody is a highly specific and reliable tool for various research applications. This antibody is produced by immunizing animals with a synthetic peptide corresponding to a specific region of the SV2B protein. It has been extensively validated for its specificity and sensitivity in detecting SV2B in various tissues and cell types.

The SV2B polyclonal antibody exhibits exceptional performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications. It enables precise and accurate detection of SV2B expression levels, allowing researchers to gain valuable insights into its role in various biological processes.

This antibody offers several advantages over other commercially available antibodies. It demonstrates minimal cross-reactivity with other SV2 isoforms, ensuring specific detection of SV2B. Additionally, it exhibits high affinity and sensitivity, enabling reliable detection even at low expression levels.

The SV2B polyclonal antibody is supplied as a purified and lyophilized product, ensuring long-term stability and ease of storage. It is compatible with a wide range of experimental conditions and can be used in various species, including human, mouse, and rat.

In summary, the SV2B polyclonal antibody is a superior research tool that provides accurate and reliable detection of SV2B expression. Its high specificity, sensitivity, and versatility make it an essential component for researchers studying the role of SV2B in various biological processes.