STAT5b Polyclonal Antibody

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

The STAT5B Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of STAT5B protein in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional sensitivity and specificity.

The STAT5B Polyclonal Antibody exhibits a strong affinity towards the STAT5B protein, enabling accurate and precise identification of this target in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its exceptional performance guarantees reliable and reproducible results, making it an indispensable tool for researchers in the field.

This antibody is produced using high-quality materials and undergoes rigorous quality control measures to ensure batch-to-batch consistency and optimal performance. Its polyclonal nature allows for enhanced sensitivity and versatility, enabling detection of even low-abundance STAT5B protein levels.

The STAT5B Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and saving valuable time in the laboratory. Its long shelf life and stability make it a cost-effective choice for long-term storage and repeated experiments.

In summary, the STAT5B Polyclonal Antibody is a reliable and highly specific tool that offers exceptional sensitivity and versatility for the detection and quantification of STAT5B protein. With its outstanding performance and ease of use, this antibody is an invaluable asset for researchers in various fields of study.