Stat3 Polyclonal Antibody

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper

The Stat3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Stat3 protein in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.

The Stat3 Polyclonal Antibody exhibits exceptional affinity and specificity towards the Stat3 protein, enabling accurate and reliable results in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes both the phosphorylated and non-phosphorylated forms of Stat3, allowing for comprehensive analysis of its activation status.

With its superior sensitivity, this antibody enables the detection of low-abundance Stat3 protein levels, making it an ideal choice for studying signaling pathways and investigating the role of Stat3 in various cellular processes. Its robust performance and minimal background noise ensure precise and reproducible results, even in complex biological samples.

The Stat3 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is compatible with a variety of sample types, including cell lysates, tissue extracts, and purified proteins, facilitating seamless integration into existing experimental protocols.

In summary, the Stat3 Polyclonal Antibody is a reliable and versatile tool for researchers in the field of molecular biology and cellular signaling. Its exceptional sensitivity, specificity, and ease of use make it an indispensable asset for elucidating the intricate mechanisms underlying Stat3-mediated cellular processes.