Stat2(Phospho Tyr631) Polyclonal Antibody

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.

The STAT2(PHOSPHO TYR631) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of phosphorylated tyrosine 631 residue on the STAT2 protein. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The STAT2(PHOSPHO TYR631) Polyclonal Antibody exhibits outstanding performance in detecting the phosphorylation status of tyrosine 631 on STAT2, a critical residue involved in signal transduction pathways. By targeting this specific phosphorylation site, researchers can gain valuable insights into the activation and regulation of STAT2-mediated signaling cascades.

This antibody is meticulously manufactured using high-quality materials and rigorous quality control measures to ensure consistent and reproducible results. It has been extensively validated for its specificity, sensitivity, and reliability, making it an ideal choice for researchers in the fields of molecular biology, cell biology, and immunology.

The STAT2(PHOSPHO TYR631) Polyclonal Antibody offers exceptional versatility, enabling its use in a wide range of experimental settings. Its compatibility with various techniques allows for comprehensive analysis of STAT2 phosphorylation, facilitating a deeper understanding of cellular signaling events and their implications in disease development and progression.

In summary, the STAT2(PHOSPHO TYR631) Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of phosphorylated tyrosine 631 residue on the STAT2 protein. With its exceptional performance and versatility, this antibody is an invaluable asset for researchers seeking to unravel the complexities of cellular signaling pathways.