SSR5 Polyclonal Antibody

Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.

The SSR5 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of SSR5 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human SSR5 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards SSR5 protein, making it an ideal tool for various applications in research and diagnostics.

The SSR5 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various assays, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes SSR5 protein from various species, including human, mouse, and rat, making it a versatile reagent for cross-species studies.

This antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum using protein A chromatography. It is provided in a liquid form, ready to use for various applications. The SSR5 Polyclonal Antibody is suitable for use in both basic and clinical research, including studies on the role of SSR5 protein in various physiological and pathological processes.

In summary, the SSR5 Polyclonal Antibody is a highly specific and sensitive immunological reagent that is ideal for the detection and quantification of SSR5 protein in various biological samples. Its high affinity and specificity make it a valuable tool for various applications in research and diagnostics.