SP6 Polyclonal Antibody

SP6 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000

The SP6 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for use in a wide range of research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the SP6 RNA polymerase promoter sequence. The resulting polyclonal antibody is purified using a combination of protein A and protein G affinity chromatography, ensuring high purity and specificity.

The SP6 Polyclonal Antibody is suitable for use in a variety of applications, including western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for use in a range of model organisms, including human, mouse, and rat. This antibody has been shown to exhibit high sensitivity and specificity, making it an ideal choice for researchers seeking a reliable and accurate tool for their experiments.

In summary, the SP6 Polyclonal Antibody is a high-quality immunological reagent that offers exceptional sensitivity and specificity for a range of research applications. Its rigorous purification process and extensive validation make it a reliable and accurate tool for researchers seeking to advance their understanding of biological systems.