SP3 Polyclonal Antibody

This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.

The SP3 Polyclonal Antibody is a highly specific and reliable tool for various immunohistochemical applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a region within the C-terminal domain of the target protein. The resulting polyclonal antibody exhibits exceptional sensitivity and specificity, making it an ideal choice for detecting and quantifying the target protein in various biological samples.

The SP3 Polyclonal Antibody has been extensively validated and optimized for use in immunohistochemistry (IHC) assays. It demonstrates excellent staining performance on formalin-fixed, paraffin-embedded tissue sections, allowing for accurate localization and visualization of the target protein. The antibody's high affinity and low background staining ensure reliable and reproducible results, enabling researchers to confidently analyze and interpret their experimental data.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. The SP3 Polyclonal Antibody is compatible with a wide range of detection systems and can be used in combination with various secondary antibodies for enhanced signal amplification.

In summary, the SP3 Polyclonal Antibody is a superior reagent for immunohistochemical studies, offering exceptional sensitivity, specificity, and reliability. Its optimized performance and ease of use make it an invaluable tool for researchers in the field of biomedical research, enabling accurate and precise detection of the target protein in various biological samples.