Smad3(Phospho Ser425) Polyclonal Antibody

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

The SMAD3(PHOSPHO SER425) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of SMAD3 protein phosphorylated at serine 425. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

SMAD3 is a critical transcription factor involved in the transforming growth factor-beta (TGF-β) signaling pathway, playing a crucial role in various cellular processes such as cell proliferation, differentiation, and apoptosis. Phosphorylation of SMAD3 at serine 425 is known to regulate its activity and downstream signaling events.

The SMAD3(PHOSPHO SER425) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated SMAD3 in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The SMAD3(PHOSPHO SER425) Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in diverse research areas, including cancer biology, developmental biology, and signal transduction studies.

Choose the SMAD3(PHOSPHO SER425) Polyclonal Antibody for its exceptional quality, reliability, and performance. It is an indispensable tool for researchers aiming to investigate the role of phosphorylated SMAD3 in cellular processes and unravel the complexities of TGF-β signaling pathway.