Smad3(Phospho Ser213) Polyclonal Antibody

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

The SMAD3(PHOSPHO SER213) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of SMAD3 protein phosphorylated at serine 213. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

SMAD3 is a critical transcription factor involved in the transforming growth factor-beta (TGF-β) signaling pathway, playing a crucial role in various cellular processes such as cell proliferation, differentiation, and apoptosis. Phosphorylation of SMAD3 at serine 213 is known to regulate its activity and downstream signaling events.

The SMAD3(PHOSPHO SER213) Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate detection and quantification of phosphorylated SMAD3 in complex biological samples.

This antibody is manufactured using high-quality materials and stringent quality control measures to ensure batch-to-batch consistency and reproducibility. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation steps.

With its superior performance and reliability, the SMAD3(PHOSPHO SER213) Polyclonal Antibody is an indispensable tool for researchers studying the TGF-β signaling pathway and its implications in various physiological and pathological conditions.