Smad1/5/9 Polyclonal Antibody

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-med

The SMAD1/5/9 polyclonal antibody is a highly specific and reliable tool for the detection and analysis of SMAD1, SMAD5, and SMAD9 proteins. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The SMAD1/5/9 polyclonal antibody is produced using state-of-the-art techniques, ensuring batch-to-batch consistency and high purity. It has been rigorously tested to ensure minimal cross-reactivity with other proteins, guaranteeing accurate and reliable results.

This antibody is suitable for use in a wide range of research areas, including developmental biology, signal transduction, and cancer research. Its versatility allows for the investigation of SMAD1, SMAD5, and SMAD9 proteins in various cell types and tissues.

The SMAD1/5/9 polyclonal antibody is provided in a convenient and ready-to-use format, allowing for easy integration into laboratory workflows. It is supplied in a liquid formulation, eliminating the need for reconstitution and ensuring optimal performance.

With its exceptional specificity, sensitivity, and reliability, the SMAD1/5/9 polyclonal antibody is an indispensable tool for researchers seeking to unravel the intricate mechanisms of SMAD1, SMAD5, and SMAD9 proteins.