SLP-76(Phospho Tyr128) Polyclonal Antibody

SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T c

The SLP-76(PHOSPHO TYR128) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of SLP-76 protein phosphorylated at tyrosine 128. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The SLP-76(PHOSPHO TYR128) Polyclonal Antibody exhibits outstanding performance in detecting the phosphorylated form of SLP-76 protein, enabling researchers to investigate the role of this specific phosphorylation event in cellular signaling pathways. With its high affinity and selectivity, this antibody allows for precise and accurate quantification of SLP-76(PHOSPHO TYR128) levels in biological samples.

This antibody is manufactured under stringent quality control measures, guaranteeing batch-to-batch consistency and reproducibility. It has been extensively validated in various experimental settings, ensuring reliable and reproducible results. The SLP-76(PHOSPHO TYR128) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation.

In summary, the SLP-76(PHOSPHO TYR128) Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of SLP-76 protein phosphorylated at tyrosine 128. Its exceptional sensitivity, specificity, and ease of use make it an invaluable asset for researchers studying cellular signaling pathways and investigating the role of SLP-76 phosphorylation in various biological processes.