SHIP-1(Phospho Tyr1021) Polyclonal Antibody

This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. The protein is also partly localized to the nucleus, where it may be involved in nuclear inositol phosphate signaling processes. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations in this gene are associated with defects and cancers of the immune system. A

The SHIP-1 (Phospho Tyr1021) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of SHIP-1 protein phosphorylated at Tyr1021. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The SHIP-1 protein plays a crucial role in regulating cellular signaling pathways, particularly in the negative regulation of phosphoinositide 3-kinase (PI3K) signaling. Phosphorylation of SHIP-1 at Tyr1021 is known to modulate its enzymatic activity and downstream signaling events. Therefore, the SHIP-1 (Phospho Tyr1021) Polyclonal Antibody serves as an invaluable tool for researchers studying the intricate mechanisms of PI3K signaling and its associated cellular processes.

This antibody exhibits exceptional specificity, as it has been extensively validated against various cell lines and tissues. It demonstrates minimal cross-reactivity with other proteins, ensuring accurate and reliable results. Additionally, the antibody is produced using high-quality materials and undergoes rigorous quality control measures to guarantee batch-to-batch consistency and reproducibility.

The SHIP-1 (Phospho Tyr1021) Polyclonal Antibody is supplied as a liquid formulation, making it convenient and easy to use. It is provided in a range of sizes to accommodate different experimental needs. The antibody is stored at -20°C, ensuring long-term stability and preserving its functionality.

In summary, the SHIP-1 (Phospho Tyr1021) Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of phosphorylated SHIP-1 protein at Tyr1021. Its exceptional sensitivity, specificity, and versatility make it an essential component in various research applications, enabling scientists to unravel the complexities of PI3K signaling and its implications in cellular processes.

The SHIP-1 (Phospho Tyr1021) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of SHIP-1 protein phosphorylated at Tyr1021. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The SHIP-1 protein plays a crucial role in regulating cellular signaling pathways, particularly in the negative regulation of phosphoinositide 3-kinase (PI3K) signaling. Phosphorylation of SHIP-1 at Tyr1021 is known to modulate its enzymatic activity and downstream signaling events. Therefore, the SHIP-1 (Phospho Tyr1021) Polyclonal Antibody serves as an invaluable tool for researchers studying the intricate mechanisms of PI3K signaling and its associated cellular processes.

This antibody exhibits exceptional specificity, as it has been extensively validated against various cell lines and tissues. It demonstrates minimal cross-reactivity with other proteins, ensuring accurate and reliable results. Additionally, the antibody is produced using high-quality materials and undergoes rigorous quality control measures to guarantee batch-to-batch consistency and reproducibility.

The SHIP-1 (Phospho Tyr1021) Polyclonal Antibody is supplied as a liquid formulation, making it convenient and easy to use. It is provided in a range of sizes to accommodate different experimental needs. The antibody is stored at -20°C, ensuring long-term stability and preserving its functionality.

In summary, the SHIP-1 (Phospho Tyr1021) Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of phosphorylated SHIP-1 protein at Tyr1021. Its exceptional sensitivity, specificity, and versatility make it an essential component in various research applications, enabling scientists to unravel the complexities of PI3K signaling and its implications in cellular processes.