Shc(Phospho Ser36) Polyclonal Antibody

This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene.

The SHC(PHOSPHO SER36) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated serine 36 residues on the SHC protein. This antibody is produced using advanced polyclonal antibody production techniques, ensuring high affinity and specificity towards the target epitope.

The SHC protein plays a crucial role in various cellular processes, including signal transduction and cell proliferation. Phosphorylation of serine 36 on the SHC protein has been implicated in the regulation of downstream signaling pathways, making it an important target for research in the field of cell biology and molecular signaling.

This polyclonal antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated serine 36 residues on the SHC protein.

The SHC(PHOSPHO SER36) Polyclonal Antibody is supplied as a liquid formulation, ensuring ease of use and convenience. It is provided in a ready-to-use format, eliminating the need for time-consuming antibody preparation steps. The antibody is also available in different sizes to accommodate various experimental requirements.

With its exceptional performance and reliability, the SHC(PHOSPHO SER36) Polyclonal Antibody is an indispensable tool for researchers studying the role of phosphorylated serine 36 residues on the SHC protein. Its high specificity and sensitivity make it an ideal choice for investigating the intricate mechanisms of cellular signaling pathways and their implications in various physiological and pathological conditions.