SCNBA Polyclonal Antibody

Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.

The SCNBA Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of the SCNBA protein. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a unique epitope of the SCNBA protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal tool for various applications in research and diagnostics.

The SCNBA Polyclonal Antibody is suitable for use in Western blotting, immunohistochemistry, and immunofluorescence assays. It has been validated for use in human, mouse, and rat samples, and has been shown to detect endogenous levels of the SCNBA protein in various tissues and cell lines. The antibody is supplied as a purified IgG fraction, and has been tested for its purity, specificity, and functionality.

The SCNBA Polyclonal Antibody is a reliable and versatile tool for the study of the SCNBA protein and its role in various biological processes. Its high sensitivity and specificity make it an essential reagent for researchers and clinicians working in the fields of neuroscience, developmental biology, and molecular biology. With its superior performance and consistent quality, the SCNBA Polyclonal Antibody is an excellent choice for any laboratory looking to advance their research and diagnostic capabilities.